Bucks and Berks Recruitment opened an office in Gainsborough House, in Thames Street, Windsor.
The firm, which was founded in Wellington Street, Slough, in 1922, as Bucks and Berks Domestic Agency, supplies local and global organisations with staff from marketing to management.
Lorena Baylis, Windsor branch manager, said: "We are delighted to open the Windsor branch. The area has a wide range of local businesses ranging from small, family-run companies to leading blue-chip organisations, plus a high calibre of candidates. We are looking forward to assisting both businesses and people's work ambitions and satisfying all their recruitment needs."
The branch will recruit staff for companies based in Windsor, Slough, Colnbrook, Staines and Egham.
The independent, family-run business also has offices in Windsor Road, Slough, St Ives Road, Maidenhead and Market Square, Marlow.